More than a half-dozen public and private sector organizations are teaming up to develop biology datasets for artificial intelligence models.
The consortium, which announced the collaboration today, is committing $1.8 billion to the project.
Studying how a cell responds to a new therapy usually requires scientists to set up a physical test environment. That can take years of work and millions of dollars. A faster, more cost-efficient approach would be to test therapies using simulated cells. A simulation doesn’t require expensive lab equipment and can theoretically be spun up in a few hours.
Ultra-detailed, highly reliable simulations that can substitute lab equipment aren’t yet available. The reason is that creating such virtual cells would require a new generation of biology-optimized AI models. Training such models would only be possible with bigger biology datasets than those presently available to scientists.
The research initiative announced today aims to produce the necessary datasets. The biggest contributor to the project is the U.S. Department of Energy, which will commit more than $500 million over five years.
Some of the funds are earmarked for microscopy equipment. The hardware will be used to collect cell measurements for AI training datasets.
The Energy Department will prioritize three imaging methods: neutron scattering, X-ray and cryo-electron microscopy. The first two methods identify the materials that make up a biological sample. Neutron scattering equipment spots light elements and their isotopes, while X-ray machines detect heavier elements. Cryo-electron microscopy, the third imaging method on the list, maps out the internal structure of cells.
The second biggest contributor to the project is Biohub, a research nonprofit backed by Mark Zuckerberg. It’s committing $400 million to the initiative. Three quarters of the funds will go toward in-house research endeavors, while the rest will support external projects.